Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate

Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate

Intermediate for Vorapaxar. Vorapaxar (trade name: Zontivity) is a thrombin receptor (protease-activated receptor, PAR-1) antagonist. Vorapaxar is a new anti-platelet drug that and is used for persons with a history of myocardial infarction (heart attack) or persons with peripheral arterial disease. Vorapaxar has been approved by the U.S Food and Drug Administration on May 5, 2014.

Specifications

Product Name:                  Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-(diphenylcarbamoyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate

Synonyms:                         N/A

CAS Number:                     900161-12-8

Molecular Weight:            490.598

Molecular Formula:          C29H34N2O5

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               O=C(O[C@@H]3C)[C@@]1([H])[C@]3([H])[C@@H]([C@@](N(C5=CC=CC=C5)C4=CC=CC=C4)=O)[C@@](CC[C@@H](NC(OCC)=O

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