(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine bis-(hydrochloride)

(3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine bis-(hydrochloride)

Intermediate for Tofacitinib. Tofacitinib (trade name Xeljanz, Jakvinus) is a janus kinase (JAK) inhibitor for the treatment of rheumatoid arthritis (RA). Tofacitinib has been approved by the U.S Food and Drug Administration in November 2012.


Product Name:                  (3R,4R)-1-benzyl-N,4-dimethylpiperidin-3-amine bis-(hydrochloride)

Synonyms:                         N/A

CAS Number:                     1062580-52-2

Molecular Weight:            291.263

Molecular Formula:          C14H24Cl2N2

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               CN[C@H]1CN(CC[C@H]1C)Cc1ccccc1.Cl.Cl

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