(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

Intermediate for Sitagliptin. Sitagliptin ( trade name Januvia) is an orally bioavailable dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type-2 diabetes. Sitagliptin has been approved by the U.S Food and Drug Administration on Oct 17, 2006.

Specifications

Product Name:                  (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

Synonyms:                         N/A

CAS Number:                     767340-03-4

Molecular Weight:            405.302

Molecular Formula:          C16H13F6N5O

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               N/C(=C\C(=O)N1CCn2c(C1)nnc2C(F)(F)F)/Cc1cc(F)c(cc1F)F

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