(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one?

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one?

Intermediate for Sitagliptin. Sitagliptin ( trade name Januvia) is an orally bioavailable dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type-2 diabetes. Sitagliptin has been approved by the U.S Food and Drug Administration on Oct 17, 2006.

Specifications

Product Name:                  (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one?

Synonyms:                         N/A

CAS Number:                     764667-65-4

Molecular Weight:            406.2868

Molecular Formula:          C16H12F6N4O2

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               O=C(Cc1cc(F)c(cc1F)F)CC(=O)N1CCn2c(C1)nnc2C(F)(F)F

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