Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Intermediate for Sitagliptin. Sitagliptin ( trade name Januvia) is an orally bioavailable dipeptidyl peptidase-4 (DPP-4) inhibitor for the treatment of type-2 diabetes. Sitagliptin has been approved by the U.S Food and Drug Administration on Oct 17, 2006.


Product Name:                  Boc-(R)-3-Amino-4-(2,4,5-trifluorophenyl)butanoic acid

Synonyms:                         N/A

CAS Number:                     486460-00-8

Molecular Weight:            333.3067

Molecular Formula:          C15H18F3NO4

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               OC(=O)C[C@@H](Cc1cc(F)c(cc1F)F)NC(=O)OC(C)(C)C

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