• (R,E)-Ethyl 5-((1,1'-biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

Intermediate for Sacubitril.  Sacubitri is a neprilysin inhibitor and is used as an antihypertensive drug in combination with valsartan. The combination drug sacubitril/valsartan(trade name: Entresto) is a treatment for heart failure. Sacubitril has been approved by the U.S Food and Drug Administration on July 7, 2015.


Product Name:                  (R,E)-Ethyl 5-((1,1'-biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

Synonyms:                         N/A

CAS Number:                     149709-59-1

Molecular Weight:            409.5242

Molecular Formula:          C25H31NO4

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               CCOC(=O)/C(=C/[C@@H](Cc1ccc(cc1)c1ccccc1)NC(=O)OC(C)(C)C)/C

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(R,E)-Ethyl 5-((1,1'-biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate

  • $208.00

  • Ex Tax: $208.00

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