AHU-377; (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride

Intermediate for Sacubitril. Sacubitril is a neprilysin inhibitor and is used as an antihypertensive drug in combination with valsartan. The combination drug sacubitril/valsartan(trade name: Entresto) is a treatment for heart failure. Sacubitril has been approved by the U.S Food and Drug Administration on July 7, 2015.


Product Name:                  AHU-377; (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride

Synonyms:                         N/A

CAS Number:                     149690-12-0

Molecular Weight:            347.8839

Molecular Formula:          C20H26ClNO2

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               CCOC([C@H](C)C[C@H](N)CC(C=C2)=CC=C2C1=CC=CC=C1)=O.Cl

AHU-377; (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride

  • $208.00
  • Ex Tax: $208.00

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