Intermediate for Sacubitril. Sacubitril is a neprilysin inhibitor and is used as an antihypertensive drug in combination with valsartan. The combination drug sacubitril/valsartan(trade name: Entresto) is a treatment for heart failure. Sacubitril has been approved by the U.S Food and Drug Administration on July 7, 2015.
Product Name: AHU-377; (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride
CAS Number: 149690-12-0
Molecular Weight:  347.8839
Molecular Formula:  C20H26ClNO2
Purity (HPLC): ≥95%
Shipping Conditions: Room temperature.
Storage Conditions: Refrigerated.
Regulatory Statement:  For Research Use Only.