(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

Intermediate for Sacubitril. Sacubitril is a neprilysin inhibitor and is used as an antihypertensive drug in combination with valsartan. The combination drug sacubitril/valsartan(trade name: Entresto) is a treatment for heart failure. Sacubitril has been approved by the U.S Food and Drug Administration on July 7, 2015.


Product Name:                  (R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

Synonyms:                         N/A

CAS Number:                     1426129-50-1

Molecular Weight:            327.4224

Molecular Formula:          C20H25NO3

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               OC[C@@H](Cc1ccc(cc1)c1ccccc1)NC(=O)OC(C)(C)C

(R)-tert-butyl (1-([1,1'-biphenyl]-4-yl)-3-hydroxypropan-2-yl)carbamate

  • $138.00
  • Ex Tax: $138.00

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