2-(2,2-Diethoxyethyl)isoindoline-1,3-dione

Intermediate for Rucaparib. Rucaparib (trade name Rubraca) is a PARP inhibitor targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1) for the treatemnt of advanced ovarian cancer. Rucaparib has been approved by the U.S Food and Drug Administration on December 19, 2016.

Specifications

Product Name:                  2-(2,2-Diethoxyethyl)isoindoline-1,3-dione

Synonyms:                         N/A

CAS Number:                     78902-09-7

Molecular Weight:            263.2926

Molecular Formula:          C14H17NO4

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               CCOC(CN1C(=O)c2c(C1=O)cccc2)OCC

2-(2,2-Diethoxyethyl)isoindoline-1,3-dione

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