Methyl 5-fluoro-2-methyl-3-nitrobenzoate

Intermediate for Rucaparib. Rucaparib (trade name Rubraca) is a PARP inhibitor targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1) for the treatemnt of advanced ovarian cancer. Rucaparib has been approved by the U.S Food and Drug Administration on December 19, 2016.

Specifications

Product Name:                  Methyl 5-fluoro-2-methyl-3-nitrobenzoate

Synonyms:                         N/A

CAS Number:                     697739-03-0

Molecular Weight:            213.1649

Molecular Formula:          C9H8FNO4

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               COC(=O)c1cc(F)cc(c1C)[N+](=O)[O-]