Intermediate for Rucaparib. Rucaparib (trade name Rubraca) is a PARP inhibitor targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1) for the treatemnt of advanced ovarian cancer. Rucaparib has been approved by the U.S Food and Drug Administration on December 19, 2016.


Product Name:                  2-Bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one

Synonyms:                         N/A

CAS Number:                     283173-80-8

Molecular Weight:            283.0994

Molecular Formula:          C11H8BrFN2O

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               Fc1cc2C(=O)NCCc3c2c(c1)[nH]c3Br


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