Methyl 6-fluoro-1H-indole-4-carboxylate

Intermediate for Rucaparib. Rucaparib (trade name Rubraca) is a PARP inhibitor targeting the DNA repair enzyme poly-ADP ribose polymerase-1 (PARP-1) for the treatemnt of advanced ovarian cancer. Rucaparib has been approved by the U.S Food and Drug Administration on December 19, 2016.

Specifications

Product Name:                  Methyl 6-fluoro-1H-indole-4-carboxylate

Synonyms:                         N/A

CAS Number:                     1082040-43-4

Molecular Weight:            193.1771

Molecular Formula:          C10H8FNO2

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               COC(=O)c1cc(F)cc2c1cc[nH]2

Methyl 6-fluoro-1H-indole-4-carboxylate

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