Lubiprostone (trade name Amitiza) is a medication used in the management of chronic idiopathic constipation, predominantly irritable bowel syndrome-associated constipation in women and opioid-induced constipation. Lubiprostone is a bicyclic fatty acid derived from prostaglandin E1 that acts by specifically activating ClC-2 chloride channels on the apical aspect of gastrointestinal epithelial cells, producing a chloride-rich fluid secretion. Lubiprostone has been approved by the U.S Food and Drug Administration on January 31, 2006.
Product Name: Lubiprostone
Synonyms: RU-0211; SPI-0211
CAS Number: 136790-76-6
Molecular Weight:  390.4666
Molecular Formula:  C20H32F2O5
Purity (HPLC): ≥95%
Shipping Conditions: Room temperature.
Storage Conditions: Refrigerated.
Regulatory Statement:  For Research Use Only.