(R)-1-Boc-3-Hydroxypiperidine

(R)-1-Boc-3-Hydroxypiperidine

Intermediate for Ibrutinib. Ibrutinib (trade name: Imbruvica) is a small Bruton's tyrosine kinase (BTK) inhibitor. Ibrutinib is used to treat B cell cancers like mantle cell lymphoma, chronic lymphocytic leukemia, and Waldenstrom's macroglobulinemia, a form of non-Hodgkin's lymphoma. Ibrutinib has been approved by the U.S Food and Drug Administration on November 19, 2013.

Specifications

Product Name:                  (R)-1-Boc-3-Hydroxypiperidine

Synonyms:                         N/A

CAS Number:                     143900-43-0

Molecular Weight:            201.265

Molecular Formula:          C10H19NO3

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               O[C@@H]1CCCN(C1)C(=O)OC(C)(C)C

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