(2R,4S)-5-((1,1'-Biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

(2R,4S)-5-((1,1'-Biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Intermediate for Sacubitril. Sacubitril is a neprilysin inhibitor and is used as an antihypertensive drug in combination with valsartan. The combination drug sacubitril/valsartan(trade name: Entresto) is a treatment for heart failure. Sacubitril has been approved by the U.S Food and Drug Administration on July 7, 2015.

Specifications

Product Name:                  (2R,4S)-5-((1,1'-Biphenyl)-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid

Synonyms:                         N/A

CAS Number:                     1012341-50-2

Molecular Weight:            383.4864

Molecular Formula:          C23H29NO4

Purity (HPLC):                     ≥95%

Shipping Conditions:         Room temperature.

Storage Conditions:           Refrigerated.

Regulatory Statement:      For Research Use Only.

SMILES:                               C[C@@H](C(=O)O)C[C@@H](Cc1ccc(cc1)c1ccccc1)NC(=O)OC(C)(C)C

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